دمتیلاسیون متوکسی متا ـ ترفنیل ها

نویسنده:

مهین احمدیان آروق

آذربایجان شرقی، ملکان، دانشگاه آزاد اسلامی واحد ملکان

چکیده

در این پژوهش, متوکسی متا- ترفنیل‌ها با استفاده از محلول بوران تری برمید در دی‌کلرومتان و دردما°C10- دمتیله شدند. متوکسی متا- ترفنیل‌‌های مورد استفاده شده ازواکنش متوکسی آریل ـ گرینیاردها با 2،6-دی کلرویدو بنزن درحلال THF و درحال رفلاکس تهیه شدند

مراجع

[1] D.Doi J., Compito-Maglizzo C., Lavallee D.K., Dealkylation of N-methyl-5,10,15,20- Tetraphenylporphine by Palladium(II) in Acetonitrile, Dimethyl Sulfoxide, and Dimethylformamide, Inorg. Chem., 23(1), p.79 (1984).

[2] Robert A., Stockland Jr., Diane L., Maher, Gordon K., Anderson, Nigam P., Demethylation of Trimethylphosphite Promoted by Dichlorodiphosphineplatinum and Palladium Complexes, Polyhedron18, p. 1067 (1999).

[3] Kasahara H., Miyazawa M., Kameoka H., O-demethylation of 7,7′-Epoxylignans by Aspergillus Niger, Phytochemistry , 43(1), p. 111 (1996).

[4] Shashi P. Singh, David E. Moody, A Radiometric TLC Assay of Liver Microsomal Dextromethorphan O-Demethylation, Journal of Pharmaceutical and Biomedical Analysis13, p. 1027 (1995).

[5] Tirthankar G., Harold H., Synthesis of Triarylbenzenes via Tandem Aryne Reactions of Aryl Grignards with Polyhalobenzenes, J. Org. Chem., 53, p. 3555 (1988).

[6] Harold H., Katsumasa H., Chi-Jen F., Synthetically Useful Aryl-Aryl Bond Formation via Grignard Generation and Trapping of Arynes. A One-Step Synthesis of p-Terphenyl and Unsymmetric Biaryls, J. Org. Chem., 50, p. 3104 (1985).

[7] Perumal R., Muthialu S., Meta-Terphenyls as Buiding Blocks for Benzimidazolophanes, Tetrahedron Letters , 38(30) , p. 5323 (1997).

[8] Arunachalam K., Perumal R., Kabaleeswaran V., Rajan S.S., Synthesis of Cyclophanes with Intra-Annular Functionality and Cage Structure, J. Org. Chem., 61, p. 5090 (1996).

[9] Perumal R., Arunachalam K., Synthesis of Functionalised Cyclophanes with Cage Structure via an Unusual Termolecular Collision, Tetrahedron Letters, 34(51), p. 8317 (1993).

[10] Furniss B.S., Hannaford A.J., Rogers V., Smith P.W.G., Tatchel A.R., “Vogel’s Text Book of Practical Organic Chemistry”, 4th edition., Longman, London and Newyork, pp. 935-937 (1989).

[11] Perrin D.D., Arm W.L.F., “Purification of Laboratory Chemical”, 3 th edition., Pergamon. Newyork, pp. 382-385 (1993).

[12] LuningU., Baumgartner H., Manthey C., Meynhardt B., Concave Reagents. 20. Sterically Shielded m-Terphenyls as Selective Agents in General Protonations, J. Org. Chem., 61, p. 7922 (1996).

[13] Ehud Keinan, Doron Eren, “An Improved Method for SN – Type Demethoxycarbonylation of Activated Esters with 4-Aminothiophenol and a Cesium Catalyst, J. Org. Chem51, P.3165 (1986).

[14] Jayaram R. Tagat, Stuart W. McCombie, Beverly E. Barton, James J., Jennifer Sh., Synthetic Inhibitors of Interleukin-6 II: 3,5-Diaryl Pyridines and Meta-Terphenyls, Bioorganic & Medicinal Chemistry Letters5(18) , p. 2143 (1995).

[15] Elmorsy S.S., Pelter A., Smith K., Trimerization of Acetone, Tetrahedron Letters , 32(33), p. 4175 (1991).

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